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CircO2

CircO2 - Nitric Oxide Energy & Circulation Support by Advanced BioNutritionals

Nitric Oxide Levels Jump 200% Higher In Just 20 Minutes

Boosts your energy… sharpens memory… increases stamina...enhances sexual performance…and helps lower blood pressure

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Star Rating
3.8 stars - 74% recommend

Discover the Secret to Boosting Nitric Oxide Fast

CircO2 is the science-backed breakthrough supplement designed to restore your body's nitric oxide production rapidly. By supporting healthier blood flow, oxygen delivery, and cognitive function, CircO2 helps you regain youthful energy, stamina, and vitality at any age. Experience the difference with a fast-dissolving lozenge that maximizes nitric oxide synthesis starting right in your mouth.

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Why You Need Nitric Oxide

Nitric oxide is the “youth molecule” your body uses to keep your blood vessels open, oxygen flowing, and brain firing at peak capacity. This powerful signaling molecule plays a pivotal role in vascular relaxation and circulation, which affects every organ and tissue. Unfortunately, as you age, nitric oxide production plummets naturally.

By age 70, your nitric oxide levels drop by about 75%; by age 80, that figure can reach up to 85%. This sharp decline contributes to fatigue, elevated blood pressure, cognitive decline including memory loss, reduced intimacy, joint discomfort, and poor circulation. Essentially, your entire vitality can suffer when nitric oxide levels wane.

  • Fatigue and reduced energy output
  • Elevated blood pressure and cardiovascular stress
  • Memory lapses and brain fog
  • Lowered sexual stamina and function
  • Joint aches and inflammation
  • Poor blood circulation and cold extremities

CircO2 fixes your nitric oxide problems in just 20 minutes. This fast-acting formula restores youthful nitric oxide signaling to support healthy arteries, brain function, energy, and overall well-being. With regular use, CircO2 encourages vibrant blood flow and oxygen delivery that rejuvenate every cell in your body.

Nitric Oxide Levels Decline with Age Chart

Why Most “Nitric Oxide” Supplements Fail

Many nitric oxide supplements focus on ingredients like L-arginine or beet juice capsules, but these approaches often fall short. The problem is understanding where nitric oxide production begins in the body: it starts in the mouth, not in the gut.

Traditional capsules must pass through digestion, reducing effectiveness. Meanwhile, the very bacteria on the tongue are critical in converting nitrates into nitric oxide. Without targeting oral bacteria activation, these supplements miss the most efficient production pathway.

Clinical research reveals that this oral activation can rapidly increase nitric oxide levels by up to 200% in just 20 minutes, which pills cannot accomplish. Most products neglect this key scientific insight, resulting in lackluster effects.

Nitric Oxide Levels Chart
Nitric Oxide Levels Chart

The MIT Breakthrough That Changes Everything

Nitric Oxide Levels Over Time Chart

MIT scientists discovered that specific bacteria residing on the tongue convert dietary nitrates into nitric oxide very rapidly. This early-stage oral activation is critical to unlocking maximum nitric oxide production.

Using this knowledge, CircO2 formulated a patented fast-dissolving lozenge that activates nitric oxide synthesis within 20 minutes, raising levels by 200% and improving blood flow by 34%. No pill, powder, or capsule on the market can claim this rapid and potent effect.

The fast absorption via the mouth and targeted ingredients ensure better cardiovascular support, oxygen delivery to tissues, and overall vitality boost. CircO2 harnesses this breakthrough to help users feel youthful, energetic, and vital again.

3 Energy-Enhancing Nutrients

Beet Root Powder

#1 Beet Root Powder

Rich in nitrates that efficiently convert to nitric oxide, beetroot powder enhances stamina and circulatory health by widening blood vessels and increasing oxygen delivery.

Hawthorn Berry Extract and others

#2 Hawthorn Berry

This botanical supports nitric oxide absorption, promotes vascular relaxation, and benefits cardiovascular function, helping maintain healthy blood pressure and heart performance.

L-Citrulline

#3 L-Citrulline

A potent amino acid precursor converting more efficiently to nitric oxide than L-arginine, it supports continuous vasodilation, enhancing energy, stamina, and recovery.

Additional essential nutrients include Vitamin B12 and Vitamin C to boost energy and nitric oxide production, Magnesium to promote vessel relaxation and heart rhythm, and Sodium Nitrite to potentiate nitric oxide formation. Together, these create a powerful system to restore nitric oxide and vascular health comprehensively.

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How CircO2 Will Transform Your Daily Life

Experience renewed energy, sharper mind, and youthful vitality
  • Boosted energy and stamina to power through your day
  • Sharper memory and improved cognitive focus
  • Healthier blood pressure through better vessel relaxation
CircO2 Benefits
  • Improved joint mobility and comfort
  • Better intimacy and sexual vitality
  • Restful sleep and refreshed mornings
  • Youthful vitality and overall body rejuvenation

About Dr. Frank Shallenberger

Dr. Frank Shallenberger is a board-certified anti-aging physician with over 44 years of medical experience. He earned his medical degree from the University of Maryland and completed postgraduate fellowship training at Mt. Zion Hospital in San Francisco. Recognized as a pioneer in the field of longevity and mitochondrial medicine, Dr. Shallenberger is also the Editor-in-Chief of multiple health newsletters reaching tens of thousands of readers. His expertise and innovative research were instrumental in developing CircO2, harnessing the science of nitric oxide to promote healthy aging and vitality.

Dr. Frank Shallenberger

Customer Testimonials

Jerome V.
Jerome V.
Verified Customer
★★★★★

I started using CircO2 tablets three weeks ago. Already I have noticed an improvement in my energy levels as well as physical and mental stamina. I‘ve decided at this stage in life that I’m going to get back to playing guitar, only better than I did as a youngster. It seems these tablets are helping because I seem to have a reservoir of mental energy left at the end of the day that I didn’t have before. I’m glad I tried this product!

Michael N.
Michael N.
Verified Customer
★★★★★

This is great stuff. I bought CircO2 about a month ago. It took about 2 weeks of taking it and I started noticing that I had more energy. I will keep taking this.

Gerald W.
Gerald W.
Verified Customer
★★★★★

My friend recommended this and I feel more energy at both the gym and at home.

Rebecca C.
Rebecca C.
Verified Customer
★★★★★

I have so much more energy and motivation to do things. I sleep better and I actually feel better. This product is so amazing. I can feel the difference in the way I feel. I actually feel like doing things that have to be done around the house.

Charlynn H.
Charlynn H.
Verified Customer
★★★★★

This really seems to help ease my restless legs. When I use it consistently, it does seem to make a positive difference.

George W G.
George W G.
Verified Customer
★★★★★

I am new to CircO2 and I've been using it for a month. I feel it is lifting me up some! Still early but I will continue to take. Looking forward to better days with CircO2.

Try CircO2 Risk-Free with Our 90-Day Guarantee

We are confident CircO2 will enhance your energy, circulation, and vitality. That's why it comes with our unique 90-Day "Down to the Last Lozenge" Money-Back Guarantee. If you're not completely satisfied for any reason, simply return the product—even if your boxes are empty—and receive a full refund. This risk-free trial lets you experience CircO2's benefits without worry. We recommend choosing multiple boxes for the best value and lasting support.

Still Undecided?

For most healthy adults, CircO2 is safe for daily use due to its natural ingredients. However, if you have low blood pressure, heart conditions, or take medications, please consult your healthcare professional before use.

Some users notice increased energy within 20 minutes of taking a lozenge. Others may require several days or weeks. Results vary based on individual age, health, and lifestyle.

CircO2 comes as a fast-dissolving lozenge placed on the tongue, activating nitric oxide production by oral bacteria converting nitrates. This oral activation enables rapid and efficient nitric oxide synthesis unattainable by pills or capsules.

Generally yes. However, users taking blood pressure medications or with cardiovascular issues should consult a healthcare provider to avoid possible interactions.

No. CircO2 is a dietary supplement manufactured in FDA-compliant facilities but is not FDA-approved to diagnose, treat, cure, or prevent any disease.

No. CircO2 supports nitric oxide and vascular health but is not a substitute for doctor-prescribed medical treatments.

CircO2 is sold exclusively through the official Advanced BioNutritionals website to ensure authenticity and eligibility for the 90-day money-back guarantee.

Results vary. CircO2’s 90-day refund guarantee allows full refund returns—even of empty boxes—providing a risk-free experience.

Allow one lozenge to dissolve fully on the tongue without chewing to maximize nitric oxide. Some users start with two lozenges daily during initial weeks, then reduce to one daily maintenance dose.

Try CircO2 Risk-Free and Save

1 Box

$49.95
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3 Boxes

$44.95/box
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6 Boxes

$41.50/box
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CircO2 Reviews

Thousands of customers report renewed energy, sharper minds, and improved well-being

"CircO2 has given me a surge of energy that lasts all day. My workouts improved dramatically and my mental clarity is sharper than ever. I highly recommend!"

Jerome V.
★★★★★
Verified Customer

"I was skeptical, but CircO2 truly works. My blood pressure has improved and I feel more youthful every day."

Michael N.
★★★★★
Verified Customer

"My joints feel less stiff and my sleep quality improved. CircO2 is now my daily go-to supplement for vitality."

Rebecca C.
★★★★★
Verified Customer

"Excellent product. My endurance and mood have improved noticeably."

Gerald W.
★★★★★
Verified Customer

"CircO2 helps with restless legs and general discomfort. I plan on using it long term."

Charlynn H.
★★★★★
Verified Customer

"I feel lifted and more vibrant since starting CircO2. It’s a life changer for those of us aging gracefully."

George W G.
★★★★★
Verified Customer

Disclaimers

  • Dr. Shallenberger receives compensation regarding Advanced BioNutritionals and CircO2 promotion.
  • These statements have not been evaluated by the Food and Drug Administration (FDA).
  • CircO2 is not intended to diagnose, treat, cure, or prevent any disease.

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